GCHFR antibody (AA 2-84)

Catalog No. ABIN7995580

The Rabbit Polyclonal anti-GCHFR antibody is suitable to detect GCHFR in samples from Human, Rat and Mouse. It has been validated for ELISA, IHC, WB, IF, FACS and ICC.

Quick Overview for GCHFR antibody (AA 2-84) (ABIN7995580)

Target: GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCHFR antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Grade: Carrier-free

Product Details anti-GCHFR Antibody

Binding Specificity: AA 2-84

Purpose: Anti-GCHFR Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-GCHFR Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GCHFR recombinant protein (Position: P2-E84).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.005 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GCHFR

Target: GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))

Alternative Name: GCHFR

Background:

Background: GTP cyclohydrolase 1 feedback regulatory protein is an enzyme that in humans is encoded by the GCHFR gene. GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.

Gene Full Name: GTP cyclohydrolase I feedback regulator

Molecular Weight: 12 kDa

Gene ID: 2644

UniProt: P30047