GIMAP5 antibody (AA 1-240) (HRP)

Catalog No. ABIN7995631

The Rabbit Polyclonal anti-GIMAP5 antibody is suitable to detect GIMAP5 in samples from Human and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for GIMAP5 antibody (AA 1-240) (HRP) (ABIN7995631)

Target: GIMAP5 (GTPase, IMAP Family Member 5 (GIMAP5))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIMAP5 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-GIMAP5 Antibody (HRP)

Binding Specificity: AA 1-240

Purpose: Anti-GIMAP5 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human GIMAP5 shares 61.7%,57.9% amino acid (aa) sequence identity with mouse,rat GIMAP5,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GIMAP5 recombinant protein (Position: M1-E240). Human GIMAP5 shares 61.7% and 57.9% amino acid (aa) sequence identity with mouse and rat GIMAP5, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GIMAP5

Target: GIMAP5 (GTPase, IMAP Family Member 5 (GIMAP5))

Alternative Name: GIMAP5

Background:

Background: This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene.

Gene Full Name: GTPase, IMAP family member 5

Gene ID: 55340

UniProt: Q96F15

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response