GIMAP5 antibody (AA 1-240) (PE)

Catalog No. ABIN7995633

This Rabbit Polyclonal antibody specifically detects GIMAP5 in FACS. It exhibits reactivity toward Human and Rat.

Quick Overview for GIMAP5 antibody (AA 1-240) (PE) (ABIN7995633)

Target: GIMAP5 (GTPase, IMAP Family Member 5 (GIMAP5))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIMAP5 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-GIMAP5 Antibody (PE)

Binding Specificity: AA 1-240

Purpose: Anti-GIMAP5 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human GIMAP5 shares 61.7%,57.9% amino acid (aa) sequence identity with mouse,rat GIMAP5,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GIMAP5 recombinant protein (Position: M1-E240). Human GIMAP5 shares 61.7% and 57.9% amino acid (aa) sequence identity with mouse and rat GIMAP5, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for GIMAP5

Target: GIMAP5 (GTPase, IMAP Family Member 5 (GIMAP5))

Alternative Name: GIMAP5

Background:

Background: This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene.

Gene Full Name: GTPase, IMAP family member 5

Gene ID: 55340

UniProt: Q96F15

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response