GAMT antibody (AA 1-236) (Fluoro550)

Catalog No. ABIN7995639

This Rabbit Polyclonal antibody specifically detects GAMT in FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for GAMT antibody (AA 1-236) (Fluoro550) (ABIN7995639)

Target: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAMT antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-GAMT Antibody (Fluoro550)

Binding Specificity: AA 1-236

Purpose: Anti-GAMT Antibody Fluoro550 Conjugated

Predicted Reactivity: Human GAMT shares 88.1%,86.8% amino acid (aa) sequence identity with mouse,rat GAMT.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GAMT recombinant protein (Position: M1-G236). Human GAMT shares 88.1% and 86.8% amino acid (aa) sequence identity with mouse and rat GAMT.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for GAMT

Target: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Alternative Name: GAMT

Background:

Background: Guanidinoacetate N-methyltransferase (EC 2.1.1.2) is an enzyme that catalyzes the chemical reaction and is encoded by gene GAMT located on chromosome 19p13.3. The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13.

Gene Full Name: guanidinoacetate N-methyltransferase

Gene ID: 2593

UniProt: Q14353