Haptoglobin antibody (AA 19-160) (APC)

Catalog No. ABIN7996018

The Rabbit Polyclonal anti-Haptoglobin antibody is suitable to detect Haptoglobin in samples from Human, Rat and Mouse. It has been validated for FACS.

Quick Overview for Haptoglobin antibody (AA 19-160) (APC) (ABIN7996018)

Target: Haptoglobin (HP)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Haptoglobin antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-Haptoglobin Antibody (APC)

Binding Specificity: AA 19-160

Purpose: Anti-Haptoglobin/HP Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Haptoglobin/HP recombinant protein (Position: V19-Q160).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Haptoglobin

Target: Haptoglobin (HP)

Alternative Name: HP

Background:

Background: Haptoglobin (HP), is a protein that in humans is encoded by the HP gene. Haptoglobin, a plasma glycoprotein that binds free hemoglobin, has a tetrameric structure of 2 alpha and 2 beta polypeptides that are covalently associated by disulfide bonds. Haptoglobin is homologous to serine proteases of the chymotrypsinogen family. A major function of haptoglobin is to bind hemoglobin (Hb) to form a stable Hp-Hb complex and thereby prevent Hb-induced oxidative tissue damage. Haptoglobin is an unusual secretory protein in that it is proteolytically processed in the endoplasmic reticulum and not in the Golgi. In clinical settings, the haptoglobulin assay is used to screen for and monitor intravascular hemolytic anemia .

Gene Full Name: haptoglobin

Gene ID: 3240

UniProt: P00738

Pathways: Transition Metal Ion Homeostasis