HAND1 antibody (C-Term) (Fluoro488)

Catalog No. ABIN7996123

The Rabbit Polyclonal anti-HAND1 antibody is suitable to detect HAND1 in samples from Human. It has been validated for FACS.

Quick Overview for HAND1 antibody (C-Term) (Fluoro488) (ABIN7996123)

Target: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAND1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-HAND1 Antibody (Fluoro488)

Binding Specificity: C-Term

Purpose: Anti-HAND1 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human HAND1 shares 90%,93.8% amino acid (aa) sequence identity with mouse,rat HAND1,respectively.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human HAND1. Human HAND1 shares 90% and 93.8% amino acid (aa) sequence identity with mouse and rat HAND1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HAND1

Target: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Alternative Name: HAND1

Background:

Background: The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.

Gene Full Name: heart and neural crest derivatives expressed 1

Gene ID: 9421

UniProt: O96004

Pathways: Tube Formation