HERC4 antibody (AA 18-1057) (Fluoro594)

Catalog No. ABIN7996675

The Rabbit Polyclonal anti-HERC4 antibody is suitable to detect HERC4 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for HERC4 antibody (AA 18-1057) (Fluoro594) (ABIN7996675)

Target: HERC4 (Hect Domain and RLD 4 (HERC4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HERC4 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-HERC4 Antibody (Fluoro594)

Binding Specificity: AA 18-1057

Purpose: Anti-HERC4 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human HERC4 shares 96.8%,97% amino acid (aa) sequence identity with mouse,rat HERC4,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HERC4 recombinant protein (Position: D18-I1057). Human HERC4 shares 96.8% and 97% amino acid (aa) sequence identity with mouse and rat HERC4, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HERC4

Target: HERC4 (Hect Domain and RLD 4 (HERC4))

Alternative Name: HERC4

Background:

Background: HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins.

Gene Full Name: HECT and RLD domain containing E3 ubiquitin protein ligase 4

Gene ID: 26091

UniProt: Q5GLZ8