HELLS antibody (AA 167-838) (APC)

Catalog No. ABIN7996755

This Rabbit Polyclonal antibody specifically detects HELLS in FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for HELLS antibody (AA 167-838) (APC) (ABIN7996755)

Target: HELLS (Helicase, Lymphoid-Specific (HELLS))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HELLS antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-HELLS Antibody (APC)

Binding Specificity: AA 167-838

Purpose: Anti-HELLS Antibody APC Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human HELLS shares 93% amino acid (aa) sequence identity with mouse HELLS.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HELLS recombinant protein (Position: N167-F838). Human HELLS shares 93% amino acid (aa) sequence identity with mouse HELLS.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HELLS

Target: HELLS (Helicase, Lymphoid-Specific (HELLS))

Alternative Name: HELLS

Background:

Background: Lymphoid-specific helicase (Lsh) is a member of the SNF2 helicase family of chromatin remodeling proteins that in humans is encoded by the HELLS gene. This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Full Name: helicase, lymphoid specific

Gene ID: 3070

UniProt: Q9NRZ9

Pathways: Chromatin Binding