HCLS1 antibody (AA 213-473) (Biotin)

Catalog No. ABIN7996759

The Rabbit Polyclonal anti-HCLS1 antibody is suitable to detect HCLS1 in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for HCLS1 antibody (AA 213-473) (Biotin) (ABIN7996759)

Target: HCLS1 (Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCLS1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-HCLS1 Antibody (Biotin)

Binding Specificity: AA 213-473

Purpose: Anti-HCLS1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HCLS1 recombinant protein (Position: N213-K473).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HCLS1

Target: HCLS1 (Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1))

Alternative Name: HCLS1

Background:

Background: Hematopoietic lineage cell-specific protein is a protein that in humans is encoded by the HCLS1 gene. Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and protein kinase binding activity. Involved in several processes, including positive regulation of intracellular signal transduction, positive regulation of protein phosphorylation, and regulation of transcription, DNA-templated. Located in cytosol, nucleus, and plasma membrane. Part of transcription regulator complex.

Gene Full Name: hematopoietic cell-specific Lyn substrate 1

Gene ID: 3059

UniProt: P14317

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Maintenance of Protein Location