HMOX2 antibody (AA 2-316) (Fluoro647)

Catalog No. ABIN7996845

This Rabbit Polyclonal antibody specifically detects HMOX2 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for HMOX2 antibody (AA 2-316) (Fluoro647) (ABIN7996845)

Target: HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMOX2 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-HMOX2 Antibody (Fluoro647)

Binding Specificity: AA 2-316

Purpose: Anti-Heme oxygenase 2/HMOX2 Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human HMOX2 shares 89%,90% amino acid (aa) sequences identity with mouse,rat HMOX2,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HMOX2 recombinant protein (Position: S2-M316). Human HMOX2 shares 89% and 90% amino acid (aa) sequences identity with mouse and rat HMOX2, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HMOX2

Target: HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

Alternative Name: HMOX2

Background:

Background: Heme oxygenase 2 (HMOX2), also known as HO-2, is an enzyme that in humans is encoded by the HMOX2 gene. It is mapped to 16p13.3. HMOX2 belongs to the heme oxygenase family. Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.

Gene Full Name: heme oxygenase 2

Sequence Similarities: Belongs to the heme oxygenase family.

Gene ID: 3163

UniProt: P30519

Pathways: Transition Metal Ion Homeostasis