HMOX2 antibody (AA 45-301) (Fluoro488)

Catalog No. ABIN7996849

The Rabbit Polyclonal anti-HMOX2 antibody is suitable to detect HMOX2 in samples from Human. It has been validated for FACS.

Quick Overview for HMOX2 antibody (AA 45-301) (Fluoro488) (ABIN7996849)

Target: HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMOX2 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-HMOX2 Antibody (Fluoro488)

Binding Specificity: AA 45-301

Purpose: Anti-Heme oxygenase 2/HMOX2 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Heme oxygenase 2/HMOX2 recombinant protein (Position: H45-A301).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HMOX2

Target: HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

Alternative Name: HMOX2

Background:

Background: Heme oxygenase 2 (HMOX2), also known as HO-2, is an enzyme that in humans is encoded by the HMOX2 gene. It is mapped to 16p13.3. HMOX2 belongs to the heme oxygenase family. Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.

Gene Full Name: heme oxygenase 2

Gene ID: 3163

UniProt: P30519

Pathways: Transition Metal Ion Homeostasis