HBA1 antibody (AA 2-142) (FITC)

Catalog No. ABIN7996907

The FITC-conjugated Rabbit Polyclonal anti-HBA1 antibody (ABIN7996907) specifically detects HBA1 in FACS. The antibody is reactive with Human samples.

Quick Overview for HBA1 antibody (AA 2-142) (FITC) (ABIN7996907)

Target: HBA1 (Hemoglobin, alpha 1 (HBA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBA1 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-HBA1 Antibody (FITC)

Binding Specificity: AA 2-142

Purpose: Anti-Hemoglobin/HBA1/HBA2 Antibody FITC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human Hemoglobin shares 85.8% amino acid (aa) sequence identity with mouse Hemoglobin.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Hemoglobin recombinant protein (Position: V2-R142). Human Hemoglobin shares 85.8% amino acid (aa) sequence identity with mouse Hemoglobin.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HBA1

Target: HBA1 (Hemoglobin, alpha 1 (HBA1))

Alternative Name: HBA1

Background:

Background: The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97 % of the total hemoglobin, alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3 % of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1, some nondeletion alpha thalassemias have also been reported.

Gene Full Name: hemoglobin subunit alpha 1

Gene ID: 3039, 3040

UniProt: P69905