HENMT1 antibody (AA 45-388) (Fluoro550)

Catalog No. ABIN7996971

This Rabbit Polyclonal antibody specifically detects HENMT1 in FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for HENMT1 antibody (AA 45-388) (Fluoro550) (ABIN7996971)

Target: HENMT1 (HEN1 Methyltransferase Homolog 1 (HENMT1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HENMT1 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-HENMT1 Antibody (Fluoro550)

Binding Specificity: AA 45-388

Purpose: Anti-HENMT1 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human HENMT1 shares 70.3%,73.3% amino acid (aa) sequence identity with mouse,rat HENMT1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HENMT1 recombinant protein (Position: Q45-D388). Human HENMT1 shares 70.3% and 73.3% amino acid (aa) sequence identity with mouse and rat HENMT1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HENMT1

Target: HENMT1 (HEN1 Methyltransferase Homolog 1 (HENMT1))

Alternative Name: HENMT1

Background:

Background: Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicerindependent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.

Gene Full Name: HEN methyltransferase 1

Gene ID: 113802

UniProt: Q5T8I9