Hephaestin antibody (AA 348-1157) (Fluoro647)

Catalog No. ABIN7997230

The Rabbit Polyclonal anti-Hephaestin antibody is suitable to detect Hephaestin in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for Hephaestin antibody (AA 348-1157) (Fluoro647) (ABIN7997230)

Target: Hephaestin (HEPH)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Hephaestin antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-Hephaestin Antibody (Fluoro647)

Binding Specificity: AA 348-1157

Purpose: Anti-Hephaestin/HEPH Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Mouse Hephaestin,HEPHshares 85.6%,96.2% amino acid (aa) sequence identity with human,rat Hephaestin,HEPH,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Hephaestin/HEPH recombinant protein (Position: E348-Q1157). Mouse Hephaestin/HEPHshares 85.6% and 96.2% amino acid (aa) sequence identity with human and rat Hephaestin/HEPH, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Hephaestin

Target: Hephaestin (HEPH)

Alternative Name: HEPH

Background:

Background: Enables ferroxidase activity. Involved in intestinal iron absorption, multicellular organismal-level iron ion homeostasis, and positive regulation of iron export across plasma membrane. Acts upstream of or within erythrocyte differentiation. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in basolateral plasma membrane. Orthologous to human HEPH (hephaestin).

Gene Full Name: hephaestin

Gene ID: 15203

UniProt: Q9Z0Z4

Pathways: Transition Metal Ion Homeostasis