HNRNPH3 antibody (AA 29-268) (Fluoro488)

Catalog No. ABIN7997322

This Rabbit Polyclonal antibody specifically detects HNRNPH3 in FACS. It exhibits reactivity toward Human.

Quick Overview for HNRNPH3 antibody (AA 29-268) (Fluoro488) (ABIN7997322)

Target: HNRNPH3 (Heterogeneous Nuclear Ribonucleoprotein H3 (2H9) (HNRNPH3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPH3 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-HNRNPH3 Antibody (Fluoro488)

Binding Specificity: AA 29-268

Purpose: Anti-HNRNPH3 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HNRNPH3 recombinant protein (Position: K29-N268).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HNRNPH3

Target: HNRNPH3 (Heterogeneous Nuclear Ribonucleoprotein H3 (2H9) (HNRNPH3))

Alternative Name: HNRNPH3

Background:

Background: Heterogeneous nuclear ribonucleoprotein H3 is a protein that in humans is encoded by the HNRNPH3 gene. This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Several alternatively spliced transcript variants have been noted for this gene, however, not all are fully characterized.

Gene Full Name: heterogeneous nuclear ribonucleoprotein H3

Gene ID: 3189

UniProt: P31942