HMGB3 antibody (N-Term) (PE)

Catalog No. ABIN7997615

The PE-conjugated Mouse Monoclonal anti-HMGB3 antibody (Clone 8H9) (ABIN7997615) specifically detects HMGB3 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for HMGB3 antibody (N-Term) (PE) (ABIN7997615)

Target: HMGB3 (High Mobility Group Box 3 (HMGB3))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This HMGB3 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: 8H9

Product Details anti-HMGB3 Antibody (PE)

Binding Specificity: N-Term

Purpose: Anti-HMG4 Antibody (monoclonal, 8H9) PE Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human HMG4, identical to the related mouse and rat sequences.

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HMGB3

Target: HMGB3 (High Mobility Group Box 3 (HMGB3))

Alternative Name: HMGB3

Background:

Background: High-mobility group protein B, also known as HMG4, is a protein that in humans is encoded by the HMGB3 gene. This gene encodes a member of a family of proteins containing one or more high mobility group DNA-binding motifs. The encoded protein plays an important role in maintaining stem cell populations, and may be aberrantly expressed in tumor cells. A mutation in this gene was associated with microphthalmia, syndromic 13. There are numerous pseudogenes of this gene on multiple chromosomes. Alternative splicing results in multiple transcript variants.

Gene Full Name: high mobility group box 3

Gene ID: 3149

UniProt: O15347