HGD antibody (AA 374-445) (HRP)

Catalog No. ABIN7998307

The Mouse Monoclonal anti-HGD antibody is suitable to detect HGD in samples from Human. It has been validated for WB, IHC and ELISA.

Quick Overview for HGD antibody (AA 374-445) (HRP) (ABIN7998307)

Target: HGD (Homogentisate 1,2-Dioxygenase (HGD))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HGD antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 2F11E1

Product Details anti-HGD Antibody (HRP)

Binding Specificity: AA 374-445

Purpose: Anti-HGD Antibody (monoclonal, 2F11E1) HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human HGD recombinant protein (Position: D374-N445).

Isotype: IgG2b

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HGD

Target: HGD (Homogentisate 1,2-Dioxygenase (HGD))

Alternative Name: HGD

Background:

Background: The HGD gene encodes homogentisate 1,2-dioxygenase (HGD), an enzyme involved in the catabolism of phenylalanine and tyrosine. This enzyme is involved in the catabolism of the amino acids tyrosine and phenylalanine. Mutations in this gene are the cause of the autosomal recessive metabolism disorder alkaptonuria. This gene is mapped to chromosome 3q21-q23 by a preliminary PCR screen of hamster/human somatic cell hybrid genomic DNA samples and by fluorescence in situ hybridization.

Gene Full Name: homogentisate 1,2-dioxygenase

Gene ID: 3081

UniProt: Q93099