HGD antibody (AA 374-445) (PE)

Catalog No. ABIN7998309

This Mouse Monoclonal antibody specifically detects HGD in FACS. It exhibits reactivity toward Human.

Quick Overview for HGD antibody (AA 374-445) (PE) (ABIN7998309)

Target: HGD (Homogentisate 1,2-Dioxygenase (HGD))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HGD antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: 2F11E1

Product Details anti-HGD Antibody (PE)

Binding Specificity: AA 374-445

Purpose: Anti-HGD Antibody (monoclonal, 2F11E1) PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human HGD recombinant protein (Position: D374-N445).

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HGD

Target: HGD (Homogentisate 1,2-Dioxygenase (HGD))

Alternative Name: HGD

Background:

Background: The HGD gene encodes homogentisate 1,2-dioxygenase (HGD), an enzyme involved in the catabolism of phenylalanine and tyrosine. This enzyme is involved in the catabolism of the amino acids tyrosine and phenylalanine. Mutations in this gene are the cause of the autosomal recessive metabolism disorder alkaptonuria. This gene is mapped to chromosome 3q21-q23 by a preliminary PCR screen of hamster/human somatic cell hybrid genomic DNA samples and by fluorescence in situ hybridization.

Gene Full Name: homogentisate 1,2-dioxygenase

Gene ID: 3081

UniProt: Q93099