HTRA1 antibody (N-Term) (Fluoro488)

Catalog No. ABIN7998380

The Fluoro488-conjugated Rabbit Polyclonal anti-HTRA1 antibody (ABIN7998380) specifically detects HTRA1 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for HTRA1 antibody (N-Term) (Fluoro488) (ABIN7998380)

Target: HTRA1 (HtrA Serine Peptidase 1 (HTRA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTRA1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-HTRA1 Antibody (Fluoro488)

Binding Specificity: N-Term

Purpose: Anti-HTRA1 Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human HTRA1, which shares 93.2% amino acid (aa) sequence identity with both mouse and rat HTRA1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HTRA1

Target: HTRA1 (HtrA Serine Peptidase 1 (HTRA1))

Alternative Name: HTRA1

Background:

Background: Serine protease HTRA1 is an enzyme that in humans is encoded by the HTRA1 gene. This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7.

Gene Full Name: HtrA serine peptidase 1

Gene ID: 5654

UniProt: Q92743

Pathways: Growth Factor Binding