HTRA4 antibody (AA 31-464) (Fluoro550)

Catalog No. ABIN7998414

This Rabbit Polyclonal antibody specifically detects HTRA4 in FACS. It exhibits reactivity toward Human.

Quick Overview for HTRA4 antibody (AA 31-464) (Fluoro550) (ABIN7998414)

Target: HTRA4 (HtrA Serine Peptidase 4 (HTRA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTRA4 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-HTRA4 Antibody (Fluoro550)

Binding Specificity: AA 31-464

Purpose: Anti-HTRA4 Antibody Fluoro550 Conjugated

Predicted Reactivity: Human HTRA4 shares 68.7%,68.9% amino acid (aa) sequence identity with mouse,rat HTRA4,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HTRA4 recombinant protein (Position: A31-D464). Human HTRA4 shares 68.7% and 68.9% amino acid (aa) sequence identity with mouse and rat HTRA4, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HTRA4

Target: HTRA4 (HtrA Serine Peptidase 4 (HTRA4))

Alternative Name: HTRA4

Background:

Background: This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.

Gene Full Name: HtrA serine peptidase 4

Gene ID: 203100

UniProt: P83105