HYAL1 antibody (N-Term) (Cy3)

Catalog No. ABIN7998522

This Rabbit Polyclonal antibody specifically detects HYAL1 in FACS. It exhibits reactivity toward Human, Mouse, Rat and Monkey.

Quick Overview for HYAL1 antibody (N-Term) (Cy3) (ABIN7998522)

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HYAL1 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-HYAL1 Antibody (Cy3)

Binding Specificity: N-Term

Purpose: Anti-Hyaluronidase-1 HYAL1 Antibody Cy3 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human HYAL1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HYAL1

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Alternative Name: HYAL1

Background:

Background: Hyaluronidase-1, also known as HYAL1 or LUCA1, is an enzyme that in humans is encoded by the HYAL1 gene. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is though to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.

Gene Full Name: hyaluronidase 1

Sequence Similarities: Belongs to the glycosyl hydrolase 56 family.

Gene ID: 3373

UniProt: Q12794

Pathways: Glycosaminoglycan Metabolic Process