HYAL3 antibody (C-Term) (Fluoro550)

Catalog No. ABIN7998557

The Fluoro550-conjugated Rabbit Polyclonal anti-HYAL3 antibody (ABIN7998557) specifically detects HYAL3 in FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for HYAL3 antibody (C-Term) (Fluoro550) (ABIN7998557)

Target: HYAL3 (Hyaluronidase-3 (HYAL3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HYAL3 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-HYAL3 Antibody (Fluoro550)

Binding Specificity: C-Term

Purpose: Anti-Hyaluronidase-3 HYAL3 Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related rat sequence by three amino acids,and different from the related mouse sequence by one amino acid.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human HYAL3, different from the related rat sequence by three amino acids, and different from the related mouse sequence by one amino acid.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HYAL3

Target: HYAL3 (Hyaluronidase-3 (HYAL3))

Alternative Name: HYAL3

Background:

Background: HYAL3 (hyaluronoglucosaminidase 3) is an enzyme that in humans is encoded by the HYAL3 gene, also known as LUCA3, Hyaluronidase-3, Lung carcinoma protein 3, LUCA-3, LUCA14, Minna14. By Northern blot analysis, expression of a 2.1-kb HYAL3 transcript that was strongest in testis and bone marrow, but relatively weak in other organs. HYAL3 encodes a predicted 417-amino acid protein. This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is though to be involved in cell proliferation, migration and differentiation. However, this protein has not yet been shown to have hyaluronidase activity. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression.

Gene Full Name: hyaluronidase 3

Sequence Similarities: Belongs to the glycosyl hydrolase 56 family.

Gene ID: 8372

UniProt: O43820

Pathways: Glycosaminoglycan Metabolic Process