HSD17B13 antibody (AA 59-300) (APC)

Catalog No. ABIN7998781

The Rabbit Polyclonal anti-HSD17B13 antibody is suitable to detect HSD17B13 in samples from Human, Rat and Mouse. It has been validated for FACS.

Quick Overview for HSD17B13 antibody (AA 59-300) (APC) (ABIN7998781)

Target: HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B13 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-HSD17B13 Antibody (APC)

Binding Specificity: AA 59-300

Purpose: Anti-HSD17B13 Antibody APC Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human HSD17B13 shares 82.6%,80.6% amino acid (aa) sequence identity with mouse,rat HSD17B13,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HSD17B13 recombinant protein (Position: R59-K300). Human HSD17B13 shares 82.6% and 80.6% amino acid (aa) sequence identity with mouse and rat HSD17B13, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HSD17B13

Target: HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

Alternative Name: HSD17B13

Background:

Background: 17β-Hydroxysteroid dehydrogenase type 13 also known as 17β-HSD type 13 is an enzyme that in humans is encoded by the HSD17B13 gene. Hydroxysteroid (17-beta) dehydrogenase 13, also designated Short-chain dehydrogenase/reductase 9 (SCDR9), which regulate the availability of steroids within various tissues throughout the body. HSD17B13 is a 300 amino acid secreted protein that is highly expressed in liver and is also detected in ovary, bone marrow, kidney, brain, lung, skeletal muscle, bladder and testis. The gene encoding HSD17B13 maps to chromosome 4, which houses nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

Gene Full Name: hydroxysteroid 17-beta dehydrogenase 13

Gene ID: 345275

UniProt: Q7Z5P4