HSD17B3 antibody (Middle Region) (Cy3)

Catalog No. ABIN7998819

This Rabbit Polyclonal antibody specifically detects HSD17B3 in FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for HSD17B3 antibody (Middle Region) (Cy3) (ABIN7998819)

Target: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B3 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-HSD17B3 Antibody (Cy3)

Binding Specificity: Middle Region

Purpose: Anti-HSD17B3 Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human HSD17B3, which shares 68.4% amino acid (aa) sequence identity with rat HSD17B3.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HSD17B3

Target: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Alternative Name: HSD17B3

Background:

Background: 17β-Hydroxysteroid dehydrogenase 3 (17β-HSD3) is an enzyme that in humans is encoded by the HSD17B3 gene and is involved in androgen steroidogenesis. This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.

Gene Full Name: hydroxysteroid 17-beta dehydrogenase 3

Gene ID: 3293

UniProt: P37058

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis