HPRT1 antibody (AA 17-186) (Fluoro647)

Catalog No. ABIN7998959

The Fluoro647-conjugated Rabbit Polyclonal anti-HPRT1 antibody (ABIN7998959) specifically detects HPRT1 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for HPRT1 antibody (AA 17-186) (Fluoro647) (ABIN7998959)

Target: HPRT1 (Hypoxanthine phosphoribosyltransferase 1 (HPRT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HPRT1 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-HPRT1 Antibody (Fluoro647)

Binding Specificity: AA 17-186

Purpose: Anti-HPRT1 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HPRT1 recombinant protein (Position: Y17-K186).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HPRT1

Target: HPRT1 (Hypoxanthine phosphoribosyltransferase 1 (HPRT1))

Alternative Name: HPRT1

Background:

Background: Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is an enzyme encoded in humans by the HPRT1 gene. The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.

Gene Full Name: hypoxanthine phosphoribosyltransferase 1

Gene ID: 3251

UniProt: P00492

Pathways: Ribonucleoside Biosynthetic Process