IdnK antibody (AA 56-182) (Biotin)

Catalog No. ABIN7999038

This Rabbit Polyclonal antibody specifically detects IdnK in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for IdnK antibody (AA 56-182) (Biotin) (ABIN7999038)

Target: IdnK (IDNK) (IdnK Gluconokinase Homolog (IDNK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IdnK antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-IdnK Antibody (Biotin)

Binding Specificity: AA 56-182

Purpose: Anti-IDNK Antibody Biotin Conjugated

Predicted Reactivity: Human IDNK shares 70.9% amino acid (aa) sequence identity with both mouse,rat IDNK.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human IDNK recombinant protein (Position: Q56-E182). Human IDNK shares 70.9% amino acid (aa) sequence identity with both mouse and rat IDNK.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IdnK

Target: IdnK (IDNK) (IdnK Gluconokinase Homolog (IDNK))

Alternative Name: IDNK

Background:

Background: C9orf103 (chromosome 9 open reading frame 103), also known as gluconate kinase, is a 187 amino acid protein that belongs to the gluconokinase gntK/gntV family and catalyzes the conversion of ATP and D-gluconate to ADP and 6-D-gluconate. Existing as three alternatively spliced isoforms, the gene encoding C9orf103 maps to human chromosome 9q21.32. Chromosome 9 consists of about 145 million bases, represents 4?% of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster.

Gene Full Name: IDNK gluconokinase

Gene ID: 414328

UniProt: Q5T6J7