IDUA antibody (AA 1-87) (FITC)

Catalog No. ABIN7999065

This Rabbit Polyclonal antibody specifically detects IDUA in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for IDUA antibody (AA 1-87) (FITC) (ABIN7999065)

Target: IDUA (Iduronidase, alpha-L- (IDUA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDUA antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-IDUA Antibody (FITC)

Binding Specificity: AA 1-87

Purpose: Anti-IDUA Antibody FITC Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human INSIG1 recombinant protein (Position: M1-R87).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for IDUA

Target: IDUA (Iduronidase, alpha-L- (IDUA))

Alternative Name: IDUA

Background:

Background: This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).

Gene Full Name: alpha-L-iduronidase

Gene ID: 3425

UniProt: P35475

Pathways: Glycosaminoglycan Metabolic Process