IKZF2 antibody (AA 1-477) (Fluoro488)

Catalog No. ABIN7999117

The Rabbit Polyclonal anti-IKZF2 antibody is suitable to detect IKZF2 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for IKZF2 antibody (AA 1-477) (Fluoro488) (ABIN7999117)

Target: IKZF2 (IKAROS Family Zinc Finger 2 (IKZF2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKZF2 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-IKZF2 Antibody (Fluoro488)

Binding Specificity: AA 1-477

Purpose: Anti-ZNFN1A2/HELIOS/IKZF2 Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ZNFN1A2/HELIOS/IKZF2 recombinant protein (Position: M1-R477).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for IKZF2

Target: IKZF2 (IKAROS Family Zinc Finger 2 (IKZF2))

Alternative Name: IKZF2

Background:

Background: Zinc finger protein Helios is a protein that in humans is encoded by the IKZF2 gene. This gene is mapped to 2q34.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Gene Full Name: IKAROS family zinc finger 2

Gene ID: 22807

UniProt: Q9UKS7