IGSF8 antibody (AA 25-426) (Biotin)

Catalog No. ABIN7999225

The Rabbit Polyclonal anti-IGSF8 antibody is suitable to detect IGSF8 in samples from Human and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for IGSF8 antibody (AA 25-426) (Biotin) (ABIN7999225)

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGSF8 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-IGSF8 Antibody (Biotin)

Binding Specificity: AA 25-426

Purpose: Anti-CD316/IGSF8 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human RAB3IP shares 89.6% amino acid (aa) sequence identity with rat RAB3IP.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RAB3IP recombinant protein (Position: F25-R426). Human RAB3IP shares 89.6% amino acid (aa) sequence identity with rat RAB3IP.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IGSF8

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Alternative Name: IGSF8

Background:

Background: Immunoglobulin superfamily member 8 is a protein that in humans is encoded by the IGSF8 gene. This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein.

Gene Full Name: immunoglobulin superfamily member 8

Gene ID: 93185

UniProt: Q969P0