Inhibin alpha antibody (AA 254-366) (Cy3)

Catalog No. ABIN7999436

The Cy3-conjugated Rabbit Polyclonal anti-Inhibin alpha antibody (ABIN7999436) specifically detects Inhibin alpha in FACS. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Inhibin alpha antibody (AA 254-366) (Cy3) (ABIN7999436)

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Inhibin alpha antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-Inhibin alpha Antibody (Cy3)

Binding Specificity: AA 254-366

Purpose: Anti-Inhibin alpha/INHA Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Inhibin alpha/INHA recombinant protein (Position: E254-I366).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Inhibin alpha

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Alternative Name: INHA

Background:

Background: Inhibin, alpha, also known as INHA, is a protein which in humans is encoded by the INHA gene. This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. Mutations in this gene may be associated with male infertility and premature ovarian failure in female human patients.

Gene Full Name: inhibin subunit alpha

Gene ID: 3623

UniProt: P05111

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion