IMMT antibody (AA 84-406) (Fluoro488)

Catalog No. ABIN7999591

The Rabbit Polyclonal anti-IMMT antibody is suitable to detect IMMT in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for IMMT antibody (AA 84-406) (Fluoro488) (ABIN7999591)

Target: IMMT (Inner Membrane Protein, Mitochondrial (IMMT))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IMMT antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-IMMT Antibody (Fluoro488)

Binding Specificity: AA 84-406

Purpose: Anti-Mitofilin/IMMT Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human PDK3 shares 97.2% amino acid (aa) sequence identity with mouse PDK3.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PDK3 recombinant protein (Position: Y84-Q406). Human PDK3 shares 97.2% amino acid (aa) sequence identity with mouse PDK3.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for IMMT

Target: IMMT (Inner Membrane Protein, Mitochondrial (IMMT))

Alternative Name: IMMT

Background:

Background: Mitochondrial inner membrane protein is a protein that in humans is encoded by the IMMT gene. IMMT (also known as mitofilin) is an inner mitochondrial membrane protein that is preferentially expressed in heart tissue and is commonly used as the marker for mitochondria. Mitofilin is known to be a critical organizer of mitochondrial cristae morphology and is indispensable for normal mitochondrial function. Three isoforms of mitofilin exist due to the alternative splicing. All three proteins of 87kD, 89kD and 80kD can be detected in immunoblot analysis with this antibody.

Gene Full Name: inner membrane mitochondrial protein

Gene ID: 10989

UniProt: Q16891