ITPA antibody (AA 1-194)

Catalog No. ABIN7999643

The Rabbit Polyclonal anti-ITPA antibody (ABIN7999643) specifically detects ITPA in WB, IHC, ELISA, FACS and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ITPA antibody (AA 1-194) (ABIN7999643)

Target: ITPA (Inosine Triphosphatase (ITPA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITPA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Grade: Carrier-free

Product Details anti-ITPA Antibody

Binding Specificity: AA 1-194

Purpose: Anti-ITPA Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human ITPA shares 89.6%,92.1% amino acid (aa) sequence identity with mouse,rat ITPA,respectively.

Characteristics: Anti-ITPA Antibody. Tested in ELISA, IF, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ITPA recombinant protein (Position: M1-A194). Human ITPA shares 89.6% and 92.1% amino acid (aa) sequence identity with mouse and rat ITPA, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ITPA

Target: ITPA (Inosine Triphosphatase (ITPA))

Alternative Name: ITPA

Background:

Background: Inosine triphosphate pyrophosphatase is an enzyme that in humans is encoded by the ITPA gene, by the rdgB gene in bacteria E.coli and the HAM1 gene in yeast S. cerevisiae, the protein is also encoded by some RNA viruses of the Potyviridae family. This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.

Gene Full Name: inosine triphosphatase

Molecular Weight: 21 kDa

Gene ID: 3704

UniProt: Q9BY32