CD51 antibody (AA 732-970)

Catalog No. ABIN8000428

The Mouse Monoclonal anti-CD51 antibody (Clone 8B10H2) (ABIN8000428) specifically detects CD51 in WB, IHC, ICC and IF. The antibody is reactive with Human samples.

Quick Overview for CD51 antibody (AA 732-970) (ABIN8000428)

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD51 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Grade: Carrier-free

Clone: 8B10H2

Product Details anti-CD51 Antibody

Binding Specificity: AA 732-970

Purpose: Anti-Integrin alpha V/ITGAV Antibody (monoclonal, 8B10H2)

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Integrin alpha V/ITGAV Antibody.(monoclonal, 8B10H2)-2. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Integrin alpha V/ITGAV recombinant protein (Position: H732-D970).

Isotype: IgG2b

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CD51

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Alternative Name: ITGAV

Background:

Background: Integrin alpha-V is a protein that in humans is encoded by the ITGAV gene. It is a member of the beta 3 integrin subfamily(cytoadhesins). The human locus for the av gene(VNRA) was previously mapped to the long arm of chromosome 2. Sims et al.(2000) localized the VNRA gene to 2q31. The gene contains 30 exons and spans over 93 kb of genomic DNA. It functions as a receptor for a group of proteins that includes vitronectin, fibrinogen, thrombospondin, and von Willebrand factor.

Gene Full Name: integrin subunit alpha V

Molecular Weight: 130 kDa

Gene ID: 3685

UniProt: P06756

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex