ILKAP antibody (AA 114-436) (Fluoro594)

Catalog No. ABIN8000708

This Rabbit Polyclonal antibody specifically detects ILKAP in FACS. It exhibits reactivity toward Human.

Quick Overview for ILKAP antibody (AA 114-436) (Fluoro594) (ABIN8000708)

Target: ILKAP (Integrin-Linked Kinase-Associated Serine/threonine Phosphatase 2C (ILKAP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ILKAP antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-ILKAP Antibody (Fluoro594)

Binding Specificity: AA 114-436

Purpose: Anti-ILKAP Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human PDK1 shares 94.7%,95.7% amino acid (aa) sequence identity with mouse,rat PDK1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PDK1 recombinant protein (Position: Y114-A436). Human PDK1 shares 94.7% and 95.7% amino acid (aa) sequence identity with mouse and rat PDK1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ILKAP

Target: ILKAP (Integrin-Linked Kinase-Associated Serine/threonine Phosphatase 2C (ILKAP))

Alternative Name: ILKAP

Background:

Background: Integrin-linked kinase-associated serine/threonine phosphatase 2C is an enzyme that in humans is encoded by the ILKAP gene. The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway.

Gene Full Name: ILK associated serine/threonine phosphatase

Gene ID: 80895

UniProt: Q9H0C8