IFITM1 antibody (N-Term) (HRP)

Catalog No. ABIN8001414

The Rabbit Polyclonal anti-IFITM1 antibody is suitable to detect IFITM1 in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for IFITM1 antibody (N-Term) (HRP) (ABIN8001414)

Target: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFITM1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-IFITM1 Antibody (HRP)

Binding Specificity: N-Term

Purpose: Anti-IFITM1 Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human IFITM1.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IFITM1

Target: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Alternative Name: IFITM1

Background:

Background: Interferon-induced Transmembrane Protein 1 (IFITM1), also called Interferon-induced Protein 17 (IFI17). IFITM1 activity is required for primordial germ cells (PGCs) transit from the mesoderm into the endoderm, and that it appears to act via a repulsive mechanism, such that PGCs avoid Ifitm1-expressing tissues. It is mapped to Chr.11 and belongs to the family of interferon-induced transmembrane proteins (Ifitm/mil/fragilis), which encodes cell surface proteins that may modulate cell adhesion and influence cell differentiation. Interferon-inducible membrane proteins of approximately 17 kDa have been suggested to play a role in the antiproliferative activity of interferons based on their pattern of induction in interferon-sensitive and -resistant cell lines and the ability of a membrane fraction enriched in 17- kDa proteins to inhibit cell growth.

Gene Full Name: interferon induced transmembrane protein 1

Sequence Similarities: Belongs to the intermediate filament family.

Gene ID: 8519

UniProt: P13164