IL36A/IL1F6 antibody (AA 6-158) (Fluoro647)

Catalog No. ABIN8001505

The Fluoro647-conjugated Rabbit Polyclonal anti-IL36A/IL1F6 antibody (ABIN8001505) specifically detects IL36A/IL1F6 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for IL36A/IL1F6 antibody (AA 6-158) (Fluoro647) (ABIN8001505)

Target: IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL36A/IL1F6 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-IL36A/IL1F6 Antibody (Fluoro647)

Binding Specificity: AA 6-158

Purpose: Anti-IL36 alpha/IL36A Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human IL36 alpha recombinant protein (Position: K6-F158).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for IL36A/IL1F6

Target: IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))

Alternative Name: IL36A

Background:

Background: Interleukin-36 alpha also known as interleukin-1 family member 6 (IL1F6) is a protein that in humans is encoded by the IL36A gene. The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients.

Gene Full Name: interleukin 36 alpha

Gene ID: 27179

UniProt: Q9UHA7

Pathways: Cancer Immune Checkpoints