Interleukin 17a antibody (AA 18-150)

Catalog No. ABIN8001979

The Rabbit Polyclonal anti-Interleukin 17a antibody (ABIN8001979) specifically detects Interleukin 17a in ELISA and IHC. The antibody is reactive with Mouse and Rat samples.

Quick Overview for Interleukin 17a antibody (AA 18-150) (ABIN8001979)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Interleukin 17a antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Grade: Carrier-free

Product Details anti-Interleukin 17a Antibody

Binding Specificity: AA 18-150

Purpose: Anti-IL-17A/Il17a Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-IL-17A/Il17a Antibody. Tested in ELISA, IHC applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived rat IL-17A/Il17a recombinant protein (Position: A18-S150).

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL, Rat

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Alternative Name: Il17a

Background:

Background: Interleukin-17A is a protein that in humans is encoded by the IL17A gene. The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Gene Full Name: interleukin 17A

Molecular Weight: 27 kDa

Gene ID: 301289

UniProt: Q61453