Interleukin 17a antibody (AA 26-158) (PE)

Catalog No. ABIN8001999

The Rabbit Polyclonal anti-Interleukin 17a antibody is suitable to detect Interleukin 17a in samples from Mouse. It has been validated for FACS.

Quick Overview for Interleukin 17a antibody (AA 26-158) (PE) (ABIN8001999)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Interleukin 17a antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-Interleukin 17a Antibody (PE)

Binding Specificity: AA 26-158

Purpose: Anti-IL17/IL17A Antibody PE Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived mouse IL-17 recombinant protein (Position: A26-A158).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Alternative Name: IL17A

Background:

Background: Interleukin-17A is a protein that in humans is encoded by the IL17A gene. The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Gene Full Name: interleukin 17A

Sequence Similarities: Belongs to the immunoglobulin superfamily. CEA family.

Gene ID: 16171

UniProt: Q62386