IL18BP antibody (AA 29-193) (Fluoro550)

Catalog No. ABIN8002159

The Fluoro550-conjugated Rabbit Polyclonal anti-IL18BP antibody (ABIN8002159) specifically detects IL18BP in FACS. The antibody is reactive with Mouse and Rat samples.

Quick Overview for IL18BP antibody (AA 29-193) (Fluoro550) (ABIN8002159)

Target: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL18BP antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-IL18BP Antibody (Fluoro550)

Binding Specificity: AA 29-193

Purpose: Anti-IL18 binding protein/Il18bp Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived mouse IL18 binding protein recombinant protein (Position: T29-A193).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for IL18BP

Target: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Alternative Name: Il18bp

Background:

Background: Interleukin-18-binding protein is a protein that in humans is encoded by the IL18BP gene. The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: interleukin 18 binding protein

Gene ID: 16068

UniProt: Q9Z0M9