IL-22 antibody (AA 34-179) (Fluoro550)

Catalog No. ABIN8002368

The Mouse Monoclonal anti-IL-22 antibody is suitable to detect IL-22 in samples from Human. It has been validated for FACS.

Quick Overview for IL-22 antibody (AA 34-179) (Fluoro550) (ABIN8002368)

Target: IL-22 (IL22) (Interleukin 22 (IL22))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-22 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Clone: 7F2

Product Details anti-IL-22 Antibody (Fluoro550)

Binding Specificity: AA 34-179

Purpose: Anti-IL22 Antibody (monoclonal, 7F2) Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human IL-22 recombinant protein (Position: A34-I179). Human IL-22 shares 81.4% amino acid (aa) sequence identity with mouse IL-22.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human IL-22 recombinant protein (Position: A34-I179). Human IL-22 shares 81.4% amino acid (aa) sequence identity with mouse IL-22.

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for IL-22

Target: IL-22 (IL22) (Interleukin 22 (IL22))

Alternative Name: IL22

Background:

Background: Interleukin-22 (IL-22), also known as ILTIF, is protein that in humans is encoded by the IL22 gene. IL-22 a member of a group of cytokines called the IL-10 family or IL-10 superfamily, a class of potent mediators of cellular inflammatory responses. Using FISH, the IL22 gene is mapped to chromosome 12q15, close to the IFNG and the herpesvirus saimiri-induced AK155 genes. IL-22 can contribute to immune disease through the stimulation of inflammatory responses, S100s and defensins. It also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. In some contexts, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by the often co-expressed cytokine IL-17A.

Gene Full Name: interleukin 22

Gene ID: 50616

UniProt: Q9GZX6