IL23A antibody (AA 20-178) (Fluoro647)

Catalog No. ABIN8002407

The Rabbit Polyclonal anti-IL23A antibody is suitable to detect IL23A in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for IL23A antibody (AA 20-178) (Fluoro647) (ABIN8002407)

Target: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL23A antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-IL23A Antibody (Fluoro647)

Binding Specificity: AA 20-178

Purpose: Anti-IL23/IL23A Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human IL23 recombinant protein (Position: R20-R178).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for IL23A

Target: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Alternative Name: IL23A

Background:

Background: Interleukin-23 subunit alpha is a protein that in humans is encoded by the IL23A gene. IL-23, also known as Interleukin-23 subunit alphainin (IL23A), is a heterodimeric cytokine consisting of two subunits, one called p40, which is shared with another cytokine, IL-12, and another called p19 (the IL-23 alpha subunit). The International Radiation Hybrid Mapping Consortium mapped the IL-23 gene to chromosome 12. IL-23 is an important part of the inflammatory response against infection. It promotes upregulation of the matrix metalloprotease MMP9, increases angiogenesis and reduces CD8+ T-cell infiltration.

Gene Full Name: interleukin 23 subunit alpha

Gene ID: 51561

UniProt: Q9NPF7

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation