IL23A antibody (N-Term) (Cy3)

Catalog No. ABIN8002410

The Rabbit Polyclonal anti-IL23A antibody is suitable to detect IL23A in samples from Mouse. It has been validated for FACS.

Quick Overview for IL23A antibody (N-Term) (Cy3) (ABIN8002410)

Target: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL23A antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-IL23A Antibody (Cy3)

Binding Specificity: N-Term

Purpose: Anti-IL23 P19/IL23A Antibody Cy3 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related rat sequence by two amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse IL23 P19, different from the related rat sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for IL23A

Target: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Alternative Name: IL23A

Background:

Background: IL-23, Interleukin-23, also known as Interleukin-23 subunit alphainin (IL23A), is a heterodimeric cytokine consisting of two subunits, one called p40, which is shared with another cytokine, IL-12, and another called p19 (the IL-23 alpha subunit). The International Radiation Hybrid Mapping Consortium mapped the IL-23 gene to chromosome 12. IL-23 is an important part of the inflammatory response against infection. It promotes upregulation of the matrix metalloprotease MMP9, increases angiogenesis and reduces CD8+ T-cell infiltration.

Gene Full Name: interleukin 23, alpha subunit p19

Sequence Similarities: Belongs to the type I cytokine receptor family. Type 3 subfamily.

Gene ID: 83430

UniProt: Q9EQ14

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation