ITSN1 antibody (AA 522-1721) (Fluoro488)

Catalog No. ABIN8003060

This Rabbit Polyclonal antibody specifically detects ITSN1 in FACS. It exhibits reactivity toward Human.

Quick Overview for ITSN1 antibody (AA 522-1721) (Fluoro488) (ABIN8003060)

Target: ITSN1 (Intersectin 1 (ITSN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITSN1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-ITSN1 Antibody (Fluoro488)

Binding Specificity: AA 522-1721

Purpose: Anti-Intersectin 1/ITSN1 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Intersectin 1/ITSN1 recombinant protein (Position: A522-P1721).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ITSN1

Target: ITSN1 (Intersectin 1 (ITSN1))

Alternative Name: ITSN1

Background:

Background: Intersectin-1 is a protein that, in humans, is encoded by the ITSN1 gene. The protein encoded by this gene is a cytoplasmic membrane-associated protein that inly coordinates endocytic membrane traffic with the actin assembly machinery. In addition, the encoded protein may regulate the formation of clathrin-coated vesicles and could be involved in synaptic vesicle recycling. This protein has been shown to interact with dynamin, CDC42, SNAP23, SNAP25, SPIN90, EPS15, EPN1, EPN2, and STN2. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been characterized so far.

Gene Full Name: intersectin 1

Gene ID: 6453

UniProt: Q15811

Pathways: Neurotrophin Signaling Pathway