INTU antibody (AA 224-935) (Cy3)

Catalog No. ABIN8003147

This Rabbit Polyclonal antibody specifically detects INTU in FACS. It exhibits reactivity toward Human.

Quick Overview for INTU antibody (AA 224-935) (Cy3) (ABIN8003147)

Target: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTU antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-INTU Antibody (Cy3)

Binding Specificity: AA 224-935

Purpose: Anti-INTU Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human INTU shares 80.5%,79.8% amino acid (aa) sequence identity with mouse,rat INTU,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human INTU recombinant protein (Position: Q224-K935). Human INTU shares 80.5% and 79.8% amino acid (aa) sequence identity with mouse and rat INTU, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for INTU

Target: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Alternative Name: INTU

Background:

Background: INTU plays a key role in ciliogenesis and embryonic development. INTU is a regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. It plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension and has an in effect on hedgehog signaling.

Gene Full Name: inturned planar cell polarity protein

Gene ID: 27152

UniProt: Q9ULD6