INTU antibody (AA 224-935)

Catalog No. ABIN8003156

This Rabbit Polyclonal antibody specifically detects INTU in WB, ELISA, FACS, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for INTU antibody (AA 224-935) (ABIN8003156)

Target: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTU antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

Grade: Carrier-free

Product Details anti-INTU Antibody

Binding Specificity: AA 224-935

Purpose: Anti-INTU Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human INTU shares 80.5%,79.8% amino acid (aa) sequence identity with mouse,rat INTU,respectively.

Characteristics: Anti-INTU Antibody. Tested in ELISA, IHC, IF, WB, Flow Cytometry applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human INTU recombinant protein (Position: Q224-K935). Human INTU shares 80.5% and 79.8% amino acid (aa) sequence identity with mouse and rat INTU, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for INTU

Target: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Alternative Name: INTU

Background:

Background: INTU plays a key role in ciliogenesis and embryonic development. INTU is a regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. It plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension and has an in effect on hedgehog signaling.

Gene Full Name: inturned planar cell polarity protein

Molecular Weight: 100 kDa

Gene ID: 27152

UniProt: Q9ULD6