IQSEC2 antibody (AA 122-1396) (APC)

Catalog No. ABIN8003230

The APC-conjugated Rabbit Polyclonal anti-IQSEC2 antibody (ABIN8003230) specifically detects IQSEC2 in FACS. The antibody is reactive with Mouse and Rat samples.

Quick Overview for IQSEC2 antibody (AA 122-1396) (APC) (ABIN8003230)

Target: IQSEC2 (IQ Motif and Sec7 Domain 2 (IQSEC2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IQSEC2 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-IQSEC2 Antibody (APC)

Binding Specificity: AA 122-1396

Purpose: Anti-IQSEC2 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human IQSEC2 shares 98.2% amino acid (aa) sequence identity with mouse IQSEC2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human IQSEC2 recombinant protein (Position: A122-M1396). Human IQSEC2 shares 98.2% amino acid (aa) sequence identity with mouse IQSEC2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for IQSEC2

Target: IQSEC2 (IQ Motif and Sec7 Domain 2 (IQSEC2))

Alternative Name: IQSEC2

Background:

Background: This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked cognitive disability. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: IQ motif and Sec7 domain ArfGEF 2

Gene ID: 23096

UniProt: Q5JU85