JOSD2 antibody (AA 1-297) (Fluoro594)

Catalog No. ABIN8003634

The Rabbit Polyclonal anti-JOSD2 antibody is suitable to detect JOSD2 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for JOSD2 antibody (AA 1-297) (Fluoro594) (ABIN8003634)

Target: JOSD2 (Josephin Domain Containing 2 (JOSD2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JOSD2 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-JOSD2 Antibody (Fluoro594)

Binding Specificity: AA 1-297

Purpose: Anti-JOSD2 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human RTCA shares 92.3% amino acid (aa) sequence identity with mouse RTCA.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RTCA recombinant protein (Position: M1-D297). Human RTCA shares 92.3% amino acid (aa) sequence identity with mouse RTCA.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for JOSD2

Target: JOSD2 (Josephin Domain Containing 2 (JOSD2))

Alternative Name: JOSD2

Background:

Background: JOSD2 (Josephin-2) is a member of the Machado-Joseph Domain (MJD) deubiquitinating enzyme family. Other family members include: Ataxin-3, Ataxin-3L, and JOSD1. JOSD2 preferentially cleaves K63-linked ubiquitin chains, with much weaker activity toward K48-linked ubiquitin chains in vitro.

Gene Full Name: Josephin domain containing 2

Gene ID: 126119

UniProt: Q8TAC2