Kallikrein 1 antibody (C-Term) (HRP)

Catalog No. ABIN8003812

The HRP-conjugated Rabbit Polyclonal anti-Kallikrein 1 antibody (ABIN8003812) specifically detects Kallikrein 1 in WB, IHC and ELISA. The antibody is reactive with Rat samples.

Quick Overview for Kallikrein 1 antibody (C-Term) (HRP) (ABIN8003812)

Target: Kallikrein 1 (KLK1)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 1 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Kallikrein 1 Antibody (HRP)

Binding Specificity: C-Term

Purpose: Anti-Kallikrein 1/Ngfg Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of rat Kallikrein 1.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Kallikrein 1

Target: Kallikrein 1 (KLK1)

Alternative Name: KLK1

Background:

Background: KLK1 (KALLIKREIN 1), also called KLKR, is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The KLK1 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The KLK1 gene contains 5 coding exons. And KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.

Gene Full Name: kallikrein 1-related peptidase B3

Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.

Gene ID: 24594

UniProt: P00758

Pathways: Complement System