Kallikrein 8 antibody (AA 33-260) (Fluoro647)

Catalog No. ABIN8003936

This Rabbit Polyclonal antibody specifically detects Kallikrein 8 in FACS. It exhibits reactivity toward Human.

Quick Overview for Kallikrein 8 antibody (AA 33-260) (Fluoro647) (ABIN8003936)

Target: Kallikrein 8 (KLK8)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 8 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-Kallikrein 8 Antibody (Fluoro647)

Binding Specificity: AA 33-260

Purpose: Anti-Kallikrein 8/KLK8 Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human Kallikrein 8 shares 74%,73.1% amino acid (aa) sequence identity with mouse,rat Kallikrein 8,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Kallikrein 8 recombinant protein (Position: V33-G260). Human Kallikrein 8 shares 74% and 73.1% amino acid (aa) sequence identity with mouse and rat Kallikrein 8, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Kallikrein 8

Target: Kallikrein 8 (KLK8)

Alternative Name: KLK8

Background:

Background: Kallikrein-8 is a protein that in humans is encoded by the KLK8 gene. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

Gene Full Name: kallikrein related peptidase 8

Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.

Gene ID: 11202

UniProt: O60259

Pathways: Complement System