KRT4 antibody (AA 170-427)

Catalog No. ABIN8004190

The Rabbit Polyclonal anti-KRT4 antibody (ABIN8004190) specifically detects KRT4 in WB, IHC, ELISA and IF. The antibody is reactive with Human samples.

Quick Overview for KRT4 antibody (AA 170-427) (ABIN8004190)

Target: KRT4 (Keratin 4 (KRT4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KRT4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Grade: Carrier-free

Product Details anti-KRT4 Antibody

Binding Specificity: AA 170-427

Purpose: Anti-Cytokeratin 4/KRT4 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Cytokeratin 4/KRT4 Antibody. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Cytokeratin 4/KRT4 recombinant protein (Position: N170-S427).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for KRT4

Target: KRT4 (Keratin 4 (KRT4))

Alternative Name: KRT4

Background:

Background: Keratin, type I cytoskeletal 4 also known as cytokeratin-4 (CK-4) or keratin-4 (K4) is a protein that in humans is encoded by the KRT4 gene. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Gene Full Name: keratin 4

Molecular Weight: 56 kDa

Gene ID: 3851

UniProt: P19013